Hospitalisations pour AVC en France pendant la pandémie de COVID-19 avant, pendant, et après le premier confinement

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Association between SARS-Cov-2 infection during pregnancy and adverse pregnancy outcomes: A re-analysis of the data reported by Wei et al. (2021).

OBJECTIVES AND BACKGROUND: Wei et al. have published a meta-analysis (MA), which aimed to evaluate the association between SARS-CoV-2 infection during pregnancy and adverse pregnancy outcomes. Using classical random-effects model, they found that SARS-CoV-2 infection was associated with preeclampsia, preterm birth and stillbirth. Performing MA with low event rates or with few studies may be challenging insofar as MA relies on several within and between-study distributional assumptions. The objective was to assess the robustness of the results provided by Wei et al. METHODS: We performed a sensitivity analysis using frequentist and Bayesian meta-analysis methods. We also estimated fragility indexes. RESULTS: For eclampsia, the confidence intervals of most frequentist models contain 1. All beta-binomial models (Bayesian) lead to credible intervals containing 1. The prediction interval, based on DL method, ranges from 0.75 to 2.38. The fragility index is 2 for the DL method. For preterm, the confidence (credible) intervals exclude 1. The prediction interval is broad, ranging from 0.84 to 20.61. The fragility index ranges from 27 to 10. For stillbirth, the confidence intervals of most frequentist models contain 1. Six Bayesian MA models lead to credible intervals containing 1. The prediction interval ranges from 0.52 to 8.49. The fragility index is 3. CONCLUSION: Given the available data and the results of our broad sensitivity analysis, we can suggest that SARS-CoV-2 infection during pregnancy is associated with preterm, and that it may be associated with preeclampsia. For stillbirth, more data are needed as none of the Bayesian analyses are conclusive.

Preventing SARS-CoV-2 transmission in rehabilitation pools and therapeutic water environments.

SARS-CoV-2 is mainly transmitted by respiratory droplets and contact with contaminated surfaces. It can be retrieved in faeces but there is no evidence of faecal-oral transmission, which is the main route of contamination in recreational waters. Standard cleaning and disinfecting procedures, microbiological control and health rules aim to prevent infectious risk regardless of the micro-organisms. In the context of progressive lockdown exit and hospital activities recovery, we assessed the risk of SARS-CoV-2 transmission in rehabilitation pools and therapeutic water environments in order to provide specific recommendations to control the spread of SARS-CoV-2 while ensuring essential rehabilitation care for patients.

Involvement of a hospital hygiene department in the management of COVID-19

The fight against the pandemic due to the new coronavirus has mobilised the entire hospital community. The hospital hygiene department was heavily involved in managing this crisis, both in terms of prevention and the implementation of protective measures, as well as screening and epidemiological monitoring. Based on its expertise, the Dijon University Hospital Centre was able to disseminate recommendations for good hygiene practices in order to protect carers and limit the spread of severe acute respiratory syndrome coronavirus 2. © 2020 z La lutte contre la pandémie due au nouveau coronavirus a mobilisé l'ensemble de la communauté hospitalière z Le service d'hygiène hospitalière s'est fortement impliqué dans la gestion de cette crise, que ce soit en termes de prévention et de mise en œuvre des mesures de protection ou de dépistage et de suivi épidémiologique z En s'appuyant sur son expertise, le centre hospitalier universitaire de Dijon a pu diffuser les recommandations de bonnes pratiques en matière d'hygiène, afin de protéger les soignants et de limiter la propagation du severe acute respiratory syndrome coronavirus 2. © 2020